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Hyundai Bioland

Hyundai Bioland Ossguide® Rosorbable Collagen Membrane

Hyundai Bioland Ossguide® Rosorbable Collagen Membrane

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OssGuide Resorbable Collagen Membrane
Hyundai Bioland · GBR Membrane

OssGuide
Resorbable Collagen Membrane

OssGuide is a guided bone regeneration membrane made of highly purified, non-cross-linked collagen — no chemical treatment, no artificial cross-linking. Its multi-pore structure promotes rapid blood supply for faster bone and soft-tissue healing, while superior tensile strength ensures reliable handling before and after hydration.

Non-Cross-Linked, Highly Purified Collagen 80.5% Porosity — Superior Tissue Integration Use Either Side — Before or After Hydration
Clinical Insight

What clinicians are saying

Real-world feedback from implantologists and oral surgeons using OssGuide in their practices.

"What sets OssGuide apart for me is the handling consistency — dry or hydrated, you get the same confident grip. I've been caught mid-surgery with membranes that become floppy after contact with blood. With OssGuide the tensile strength holds, adaptation to irregular buccal defects is reliable, and I can suture without worrying about tearing at the margin."

Dehiscence · Horizontal Augmentation · Handling Reliability

"The resorption timeline is what makes OssGuide stand out clinically. I need the membrane to maintain space through the early mineralisation phase — typically 8 to 12 weeks — and OssGuide consistently does that. At secondary surgery, the collagen architecture is still intact, which tells me the scaffold has done its job without premature degradation."

Ridge Preservation · Space Maintenance · Resorption Profile
Resources

Clinical Documentation

Indications

When to use OssGuide

OssGuide covers the full range of GBR indications — from socket management at the time of extraction to complex horizontal and vertical ridge augmentation.

Dehiscence & Fenestration Defects — Covers buccal bone defects around implants. Excellent contouring to irregular surfaces ensures full coverage and maintained space for new bone formation.
Horizontal Bone Augmentation — Used in combination with bone graft material to reconstruct horizontally deficient ridges. High porosity supports rapid vascularisation and integration of the graft.
Ridge Preservation (Socket Sealing) — Applied immediately after extraction to seal the socket, preserve buccal plate volume, and maintain ridge dimensions ahead of implant placement.
Ridge Reconstruction — Supports augmentation around immediate implant placement in sites with large bone defects, maintaining volume and soft-tissue contour through the healing phase.
Sinus Perforation Repair — Placed into the sinus cavity to repair membrane perforations during lateral sinus lift, providing a stable biological barrier to prevent graft displacement.
Soft-Tissue Support & Wound Closure — Facilitates primary closure over augmented sites. The multi-pore structure integrates with overlying soft tissue, reducing the incidence of dehiscence post-operatively.
Scientific Evidence

Test data & product comparison

OssGuide performance validated against a comparable collagen membrane (Product B) across three key clinical parameters.

① High Tensile Strength & Suture Resistance — Improved Handling

Tensile Strength Test

Strength of Suture Resistance Test

Before Hydration

After Hydration

  • Superior tensile strength prevents tearing during manipulation and enables stable adhesion to the bone defect area
  • Can be used indiscriminately on either side, before or after hydration — no need to distinguish membrane orientation
  • Non-cross-linked Type I collagen structure provides high suture resistance with lower risk of detachment

② Support New Bone Formation & Soft-Tissue Healing

Pore Structure

Soft Tissue Healing

  • Multi-pore structure enhances rapid blood supply to the defect site, expediting new bone generation
  • Higher porosity (80.5% ± 6.08% vs. 65.7% ± 2.8%) and greater total pore area (16.2 vs. 10.5 m²/g) compared to a comparable membrane
  • Lower incidence of soft tissue dehiscence — the porous architecture promotes fibrovascular ingrowth and stable wound closure

③ Bioresorbable Scaffold & Prolonged Barrier Function

Collagen Membrane Resorption Test (Canine Model)
— MT Staining

  • OssGuide collagen fibres maintained initial thickness and length throughout the entire 12-week observation period
  • Product B fibres became shorter and thinner from week 4 onward, with markedly thinner fibrils by week 12
  • Biodegradable and fully absorbed within approximately 24 weeks after implantation
  • Facilitates soft-tissue healing and effectively maintains the ridge as a barrier
Available Sizes

Choose the right size for your indication

OssGuide is available in three sizes to cover single-tooth defects through to large augmentation sites. All sizes can be trimmed to fit.

OssGuide TG-1 15x20mm
TG-1
15 × 20 mm
Single-tooth defects
Fenestration
Small dehiscence
OssGuide TG-2 20x30mm
TG-2
20 × 30 mm
Standard dehiscence
Ridge preservation
Sinus perforation
OssGuide TG-3 30x40mm
TG-3
30 × 40 mm
Horizontal augmentation
Ridge reconstruction
Large defects
Clinical Cases

Real-world clinical outcomes

Cases courtesy of Hyundai Bioland — demonstrating OssGuide performance across a range of GBR indications.

Dehiscence Defect

Large buccal dehiscence around implants — membrane application and 4-month follow-up

Fenestration Defect

Large buccal dehiscence and fenestration — stable soft tissue and osseous integration at 4 months

Horizontal Augmentation

Horizontal bone defect — new bone formation confirmed at secondary surgery

Ridge Preservation

Immediate implant placement with OssGuide for ridge augmentation — stable soft tissue and bone at 4 months

Specifications

Technical specifications

Device type Resorbable guided bone regeneration (GBR) membrane
Material Highly purified Type I collagen — non-cross-linked, no chemical treatment
Available sizes TG-1: 15 × 20 mm · TG-2: 20 × 30 mm · TG-3: 30 × 40 mm
Orientation Either side — no distinction required before or after hydration
Porosity 80.5% ± 6.08%
Tensile strength (dry) 6.04 MPa
Suture pullout strength (dry) 4.35 N
Resorption period Approximately 24 weeks after implantation
Origin Made in Korea
Clinical Tips

Getting the most from OssGuide

Practical guidance for predictable GBR outcomes.

1
No need to identify which side faces the bone. OssGuide can be placed with either surface against the defect — before or after hydration — without compromising barrier function or tissue integration. This eliminates a common source of intra-operative confusion, particularly in confined surgical fields.
2
Hydration improves pliability for complex defect geometries. For irregular buccal contours or saddle-shaped defects, brief contact with saline enhances flexibility and surface adaptation. The membrane retains its tensile strength after hydration — suturing, pin fixation, or tacking remain reliable.
3
Size selection should allow 2–3 mm overlap beyond the defect margin. TG-1 (15 × 20 mm) suits single-tooth fenestration and small dehiscence defects. TG-2 (20 × 30 mm) covers most standard implant-level GBR cases. TG-3 (30 × 40 mm) is preferred for horizontal augmentation, large ridge reconstruction, and multi-implant sites. All sizes can be trimmed chairside.
4
Achieve tension-free primary closure over the membrane. OssGuide supports soft-tissue healing, but primary closure remains the strongest predictor of GBR success. Periosteal releasing incisions should be made where necessary to avoid pressure on the membrane surface during the early healing phase.
5
Plan for a 24-week resorption window. OssGuide maintains its collagen scaffold architecture through 12 weeks — the critical bone mineralisation period — and fully resorbs by approximately 24 weeks. Second-stage surgery for implant uncovering can typically be planned from 4 months post-operatively without expectation of residual membrane.
⚠ Clinical Notice: OssGuide is a CE-marked medical device for use by trained dental surgeons in guided bone regeneration procedures. Single unit per patient. Store in a cool, dry location away from direct sunlight. Do not use if packaging is damaged or sterility is compromised. Refer to the Instructions for Use for full indications, contraindications, and handling guidelines.